Choose Wisely… IVF Therapy & the Critically-Ill Patient

Dr. Michael Winters returns to discuss IV Fluid resuscitation in the critically ill patient.  Should we abandon Normal Saline? What other options are available?  What is a balanced fluid, and which patient might benefit from a fluid with a lower SID? Learn the answers, and become an expert in one of the most common therapies given in the ICU by watching this fabulous review by Dr. Winters.

Pearls

  1. Myth: It takes approximately 3x as much crystalloid when compared to colloid to achieve the same amount of intravascular volume expansion in IVF resuscitation.  Fact:  In the critically-ill patient, there is a degradation of endothelial glycocalyx lining the vascular system reducing the ratio to as low as 1.3:1.  
  2. The pH of a IVF does not determine the effect on the patient’s acid-base status.  What does?
    • Strong ion difference
    • Weak acid content (albumin, phosphate)
  3. The ideal balanced solution has a SID of about 24 (roughly equal to a normal bicarbonate level)
  4. Lactated ringers contains about 130 mEq of sodium, so avoid giving LR to patients with:
    • Traumatic brain injury
    • Hyponatremia
    • Cerebral edema
  5. It is recommended that patients diagnosed with SBP should receive albumin (1.5 g/kg of 25% solution) within 6 hours of diagnosis.

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