Angela's Story – Resus of an Amniotic Fluid Embolism Induced DIC with TEG

About a month ago, a young woman by the name of Angela Knight reached out to let us to let us know that she believes the use of the thrombelastogram (TEG) saved her life.  We were intrigued to say the least. Angela was preparing to give birth to her second son when she suddenly went into acute respiratory failure, a brief cardiac arrest, then subsequently progressed to DIC.

This all took place at Memorial Hospital in South Bend, Indiana – the home of Dr. Mark Walsh and Dr. Maury Hurwich. Dr. Walsh is no stranger to the Maryland CC Project and is a proud enthusiast of the TEG.  Dr. Hurwich is an anesthesiologist at Memorial who has also played a major role in bringing the TEG to the bedside and incorporating it into hospital wide resuscitation protocols.

Walsh - TEG Image

Dr. Walsh’s suggested TEG based – goal directed blood component therapy based on work by Holcomb & Tapia.

Goal Directed Blood Component Therapy

So what do you think?  Is the TEG ready for all forms of hemorrhagic shock & coagulopathy?  Tell us your thoughts below!

 

Just so everyone knows, we do not have any disclosures with the TEG or any corporate ties.  We do this for free.  We love good medicine.

Suggested Reading

  1. Walsh M, Jbara M, et al. Thromboelastographic goal-directed blood component therapy for severe hemorrhage. Blood Bulletin. March, 2014.
  2. Jansen AJ, Van rhenen DJ, Steegers EA, Duvekot JJ. Postpartum hemorrhage and transfusion of blood and blood components. Obstet Gynecol Surv. 2005;60(10):663-71.
  3. Gist RS, Stafford IP, Leibowitz AB, Beilin Y. Amniotic fluid embolism. Anesth Analg. 2009;108(5):1599-602.
  4. Burtelow M, Riley E, Druzin M, Fontaine M, Viele M, Goodnough LT. How we treat: management of life-threatening primary postpartum hemorrhage with a standardized massive transfusion protocol. Transfusion. 2007;47(9):1564-72.
  5. Thachil J, Toh CH. Disseminated intravascular coagulation in obstetric disorders and its acute haematological management. Blood Rev. 2009;23(4):167-76.
  6. Tapia NM, Chang A, Norman M, et al. TEG-guided resuscitation is superior to standardized MTP resuscitation in massively transfused penetrating trauma patients. J Trauma Acute Care Surg. 2013;74(2):378-85.
  7. Holcomb JB, Minei KM, Scerbo ML, et al. Admission rapid thrombelastography can replace conventional coagulation tests in the emergency department: experience with 1974 consecutive trauma patients. Ann Surg. 2012;256(3):476-86.

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