Pragmatic Critical Care Trials Embedded in Practice

Dr. Matthew Prekker discusses the role of pragmatic clinical trials in improving emergency airway management. He details the collaborative efforts of the Pragmatic Critical Care Research Group (PCCRG), a multi-center network dedicated to conducting comparative effectiveness research on routine medical interventions. By analyzing large-scale studies like the DEVICE and BEAM trials, the presentation highlights how video laryngoscopy and the use of a bougie can significantly increase first-pass intubation success in critically ill patients. Dr. Prekker also addresses the regulatory challenges and logistical frameworks required to perform high-quality research at the point of care, particularly regarding informed consent in emergency settings. Ultimately, he emphasizes using real-world data to refine clinical guidelines and standardize best practices for high-risk procedures.

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