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A 60 year old female is just admitted to your ICU and is post-op from a C5 posterior cervical decompression & corpectomy for a C5 burst fracture. Â Based on her work-up in the resuscitation room, it appears that she has multiple pathologic spine fractures, and newly diagnosed metastatic cancer. Â You take a look at the ventilator and this is what you see.
What is the vent abnormality and what is your differential diagnosis?[/tab]
[tab]Answer: Ineffective Triggering
This patient is experiencing an inability to trigger the ventilator to provide a positive pressure breath over the set rate. Â Ineffective triggering is the most common type of ventilator asynchrony, and the differential diagnosis includes:
- Auto peep (the most common cause)
- Neuromuscular weakness
- Improper ventilator settings
Auto peep is the most common cause of ineffective triggering and will often occur as a patient cannot create enough inspiratory force to overcome their own intrinsic peep (PEEPi). Â Patients requiring a prolonged period of mechanical ventilation and chronic obstructive lung disease have a higher incidence of ineffective triggering, most likely due to their reduced respiratory mechanics and muscle strength. Â Patients who are overly sedated, have cervical spine injuries, or diaphragmatic weakness may also experience ineffective triggering if they cannot create enough of a negative inspiratory force to trigger the vent to deliver a positive pressure breath. Lastly, improper trigger sensitivities may make it difficulty for the ventilator to sense when the patient is attempting to take a spontaneous breath.
References
- Chao DC, Scheinhorn DJ, Stearn-hassenpflug M. Patient-ventilator trigger asynchrony in prolonged mechanical ventilation. Chest. 1997;112(6):1592-9.
- Esteban A, Anzueto A, AlÃa I, et al. How is mechanical ventilation employed in the intensive care unit? An international utilization review. Am J Respir Crit Care Med. 2000;161(5):1450-8.
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